Search on:
PANCREATIC POLYPEPTIDE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Pancreatic Polypeptide
Descriptor
Spanish
:
Polipéptido Pancreático
Descriptor
Portuguese
:
Polipeptídeo Pancreático
Synonyms
English
:
Pancreatic Polypeptide (PP)
Pancreatic Polypeptide Hormone
Pancreatic Prohormone
Tree Number:
D06.472.699.587.700
D12.644.400.600
D12.644.548.586.700
D12.776.631.650.600
Definition
English
:
A 36-amino acid pancreatic hormone that is secreted mainly by
endocrine cells
found at the periphery of the
ISLETS OF LANGERHANS
and adjacent to cells containing
SOMATOSTATIN
and
GLUCAGON
.
Pancreatic polypeptide
(PP), when administered peripherally, can suppress gastric secretion,
gastric emptying
, pancreatic enzyme secretion, and
appetite
. A lack of
pancreatic polypeptide
(PP) has been associated with
OBESITY
in rats and mice.
Pharmacological Action:
Gastrointestinal Agents
Hormones
History Note
English
:
79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
22598
Unique Identifier:
D010191
Occurrence in VHL
:
Similar:
DeCS